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Transcription factor 15 (TCF-15) also known as Paraxis, is a protein that in humans is encoded by the TCF15 gene.cite-ref-entrez-5-0[5]

• Function

• References

• Further reading

Transcription factor 15 is found in the nucleus and is involved in the early transcriptional regulation of patterning of the mesoderm, and has a key role in somitogenesis.cite-ref-uniprot-6-0[6] The encoded basic helix-loop-helix protein requires dimerization with another basic helix-loop-helix protein for efficient DNA binding. [provided by RefSeq, Jul 2008].

cite-note-refgrch38ensembl-11. GRCh38: Ensembl release 89: ENSG00000125878 – Ensembl, May 2017

cite-note-refgrcm38ensembl-22. GRCm38: Ensembl release 89: ENSMUSG00000068079 – Ensembl, May 2017

cite-note-33. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

cite-note-44. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

cite-note-entrez-55. ↑ "Entrez Gene: Transcription factor 15". Retrieved 2017-11-09.

cite-note-uniprot-66. ↑ "TCF15". UniProt. Retrieved 29 June 2025.

• citerefguozhaodongsun2009Guo P, Zhao KW, Dong XY, Sun X, Dong JT (2009). "Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells". J. Biol. Chem. 284 (27): 18184–93. doi:10.1074/jbc.M109.007096. PMC 2709394. PMID 19419955.

• citerefcoppiellocollantessirerol-piquervandenwijngaert2015Coppiello G, Collantes M, Sirerol-Piquer MS, Vandenwijngaert S, Schoors S, Swinnen M, Vandersmissen I, Herijgers P, Topal B, van Loon J, Goffin J, Prósper F, Carmeliet P, García-Verdugo JM, Janssens S, Peñuelas I, Aranguren XL, Luttun A (2015). "Meox2/Tcf15 heterodimers program the heart capillary endothelium for cardiac fatty acid uptake". Circulation. 131 (9): 815–26. doi:10.1161/CIRCULATIONAHA.114.013721. hdl:10550/105619. PMID 25561514.